Porcine Corticosteroid-Binding Globulin: Binding Properties and Levels in Stress-Susceptible Swine
نویسندگان
چکیده
منابع مشابه
Effects of thermal stress, breed and stress susceptibility on corticosteroid binding globulin in swine.
Day-to-day variations in binding capacity and association constant of corticosteroid binding globulin (CBG) and plasma cortisol levels were determined in crossbred gilts maintained under controlled or fluctuating environmental temperature and humidity regimes. In addition, effect of breed and stress susceptibility of swine on CBG properties and plasma cortisol concentrations were also studied. ...
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Recently, much evidence has indicated that sex hormone-binding globulin (SHBG) and corticosteroid-binding globulin (CBG) play a role in the intracellular action of sex steroids in target cells. In the present work, expression of SHBG mRNA and CBG mRNA was demonstrated in tissues of human normal endometrium and pelvic endometriosis, using the reverse transcription-polymerase chain reaction (RT-P...
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Specific binding sites for corticosteroid-binding globulin were detected on membranes prepared from human prostates. The binding sites are typical of membrane receptors: they are saturable and specific and have high affinity. There was little specific binding at 4 degrees C and 23 degrees C. Maximal specific binding was obtained at 37 degrees C. Scatchard analysis revealed the presence of a sin...
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Glucocorticoids are known to be involved in myocardial regeneration and destruction. Cardiomyocytes are mostly devoid of nuclear glucocorticoid receptors (GRs) and it is generally assumed that effects of adrenal steroids in heart are mediated through the mineralocorticoid receptor (MR). Here we used immunocytochemistry to study localization of corticosteroid binding globulin (CBG) in semithin s...
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Exogenous administration of glucocorticoids is a widely used and efficient tool to investigate the effects of elevated concentrations of these hormones in field studies. Because the effects of corticosterone are dose and duration-dependent, the exact course of plasma corticosterone levels after exogenous administration needs to be known. We tested the performance of self-degradable corticostero...
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ژورنال
عنوان ژورنال: Journal of Animal Science
سال: 1974
ISSN: 0021-8812,1525-3163
DOI: 10.2527/jas1974.3861224x